Talk:Data Sizing Best Practices Recommendation
The CDER Common Data Standards Issues Document clearly indicates that a large lab dataset (> 1 Gb) should be split, that both the split and full datasets should be submitted and that a /SPLIT subdirectory should be used. I submitted a question to cder-edata in 2012 and received confirmation that this guidance applies to all large datasets. Has the CSS workgroup's recommendation to submit only the split files been vetted with CDER? Will CDER guidance be updated?